Organic Chemistry. Clayden J. et al.

Oxford: 2000, 1512p. Oxford: 2012, 2nd, 1261p.

Inspiring and motivating students from the moment it published, Organic Chemistry has established itself in just one edition as the student's choice of an organic chemistry text. The second edition refines and refocuses Organic Chemistry to produce a text that is even more student-friendly, coherent, and logical in its presentation than before. Like the first, the second edition is built on three principles: An explanatory approach, through which the reader is motivated to understand the subject and not just learn the facts; A mechanistic approach, giving the reader the power to understand compounds and reactions never previously encountered; An evidence-based approach, setting out clearly how and why reactions happen as they do, giving extra depth to the reader's understanding. The authors write clearly and directly, sharing with the reader their own fascination with the subject, and leading them carefully from topic to topic. Their honest and open narrative flags pitfalls and misconceptions, guiding the reader towards a complete picture of organic chemistry and its universal themes and principles.

Format: pdf ( 2000, 1512p.)

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Format: pdf ( 2012, 2nd, 1261p.)

Size: 15,6 Mb

View, download: yandex.disk

Russian language: Органическая химия. Клайден Дж., Гривз Н., Уоррен С. др. (2001, 1927с.)

Table of Contents ( 2000 )
1 What is organic chemistry? 1
Organic chemistry and this book 16
2 Organic structures 19
3 Determining organic structures 47
4 Structure of molecules 81
5 Organic reactions 113
6 Nucleophilic addition to the carbonyl group 135
7 Delocalization and conjugation 151
8 Acidity, basicity, and pKa 181
9 Using organometallic reagents to make C-C bonds 209
10 Conjugate addition 227
11 Proton nuclear magnetic resonance 243
12 Nucleophilic substitution at the carbonyl (C=0) group 279
13 Equilibria, rates, and mechanisms: summary of mechanistic principles 305
14 Nucleophilic substitution at C=0 with loss of carbonyl oxygen 339
15 Review of spectroscopic methods 361
16 Stereochemistry 381
17 Nucleophilic substitution at saturated carbon 407
18 Conformational analysis 447
19 Elimination reactions 477
20 Electrophilic addition to alkenes 503
21 Formation and reactions of enols and enolates 523
22 Electrophilic aromatic substitution 547
23 Electrophilic alkenes 581
24 Chemoselectivity: selective reactions and protection 615
25 Synthesis in action 643
26 Alkylation of enolates 663
27 Reactions of enolates with aldehydes and ketones: the aldol reaction 689
28 Acylation at carbon 723
29 Conjugate addition of enolates 749
30 Retrosynthetic analysis 771
31 Controlling the geometry of double bonds 803
32 Determination of stereochemistry by spectroscopic methods 823
33 Stereoselective reactions of cyclic compounds 851
34 Diastereoselectivity 881
35 Pericyclic reactions 1: cycloadditions 905
36 Pericyclic reactions 2: sigmatropic and electrocyclic reactions 943
37 Rearrangements 969
38 Fragmentation 1003
39 Radical reactions 1019
40 Synthesis and reactions of carbenes 1053
41 Determining reaction mechanisms 1079
42 Saturated heterocycles and stereoelectronics 1121
43 Aromatic heterocycles 1: structures and reactions 1147
44 Aromatic heterocycles 2: synthesis 1185
45 Asymmetric synthesis 1219
46 Organo-main-group chemistry I: sulfur 1247
47 Organo-main-group chemistry II: boron, silicon, and tin 1277
48 Organometallic chemistry 1311
49 The chemistry of life 1345
50 Mechanisms in biological chemistry 1381
51 Natural products 1413
52 Polymerization 1451
53 Organic chemistry today 1481 Index 1491

Organic chemistry and you
You are already a highly skilled organic chemist. As you read these words, your eyes are using an organic compound (retinal) to convert visible light into nerve impulses. When you picked up this book, your muscles were doing chemical reactions on sugars to give you the energy you needed. As you understand, gaps between your brain cells are being bridged by simple organic molecules (neuro-transmitter amines) so that nerve impulses can be passed around your brain. And you did all that without consciously thinking about it. You do not yet understand these processes in your mind as well as you can carry them out in your brain and body. You are not alone there. No organic chemist, however brilliant, understands the detailed chemical working of the human mind or body very well. We, the authors, include ourselves in this generalization, but we are going to show you in this book what enormous strides have been taken in the understanding of organic chemistry since the science came into being in the early years of the nineteenth century. Organic chemistry began as a tentative attempt to understand the chemistry of life. It has grown into the confident basis of vast multinational industries that feed, clothe, and cure millions of people without their even being aware of the role of chemistry in their lives. Chemists cooperate with physicists and mathematicians to understand how molecules behave and with biologists to understand how molecules determine life processes. The development of these ideas is already a revelation at the beginning of the twenty-first century, but is far from complete. We aim not to give you the measurements of the skeleton of a dead science but to equip you to understand the conflicting demands of an adolescent one.